The Curbsiders Internal Medicine Podcast

#24 Treating OUD in the Fentanyl Era: ASAM Treatment Week with Dr. Melissa Weimer

Oct. 17, 2023

Keep saving lives by prescribing methadone and buprenorphine. Learn how initiations of each have changed in the era of high-potency synthetic opioids (HPSOs) like fentanyl and how to continue to provide person-centered care to people with opioid use disorder. We’re joined by Dr Melissa Weimer, @DrMelissaWeimer (Yale University). This episode is in honor of National Addiction Treatment Week (

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By listening to this episode and completing CME, this can be used to count towards the new DEA 8-hr requirement on substance use disorders education.

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  • Producers: Shawn Cohen MD,  Kenneth Morford MD
  • Writer: Carolyn Chan MD MHS
  • Show Notes: Shawn Cohen MD
  • Infographic and Cover Art: Kenneth Morford MD
  • Hosts: Carolyn Chan MD. MHS Shawn Cohen MD, Natalie Stahl MD, Kenneth Morford MD
  • Reviewer: Kento Sonoda MD
  • Showrunner: Carolyn Chan, MD, MHS
  • Technical Production: PodPaste
  • Guest: Melissa Weimer DO MCR

Show Segments

  • Intro, disclaimer, guest bio 00:00
  • Guest one-liner 05:02
  • National Addiction Treatment Week  06:00
  • Case from Kashlak; Definitions 08:30
  • Starting methadone  11:01
  • Common methadone pitfalls 15:00
  • Buprenorphine precipitated opioid withdrawal  23:50
  • High-dose buprenorphine 32:20
  • Treating buprenorphine precipitated withdrawal 36:50
  • Low-dose buprenorphine 41:50
  • Maintenance dose of buprenorphine 48:15
  • ER buprenorphine 49:00
  • Take home points 53:31 neither hosts nor alters podcast files. All content © its respective owners.