The Curbsiders Internal Medicine Podcast

#422 LIVE! Inpatient Management of Sickle Cell Crisis, Acute Pain, RBC Transfusions & Acute Chest Syndrome

Jan. 15, 2024

Learn practical tips for the inpatient management of patients with sickle cell disease and vaso-occlusive crisis from guest, Dr. Yoo Mee Shin (Emory). We cover acute pain management including adjuvant therapies, IV fluids, oxygen therapy, the management of acute chest syndrome, and when to perform simple vs exchange transfusions. Key takeaways include the importance of early triage and analgesia, addressing misconceptions about opioid use disorder in patients with sickle cell disease, and recognizing complications of vaso-occlusive crises.

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Show Segments

  • 00:00 Intro
  • 01:27 Getting to know our guest
  • 07:48 Case Presentation and Initial Management of Sickle Cell Disease (SCD)
  • 13:46 Misconceptions about opioid use disorder and sickle cell
  • 17:02 Management of Acute Pain in Sickle Cell Disease
  • 25:46 Adjuvant therapy for pain
  • 29:04 Transition to outpatient care
  • 32:46 General admission orders for sickle cell
  • 38:44 Management of Acute Chest Syndrome
  • 42:01 Simple vs exchange transfusion
  • 47:08 Transfusion in preoperative and pregnant patients
  • 48:03 Transitions and follow-up care
  • 49:35 Key takeaways and Outro


  • Written and Produced by:  Matthew Watto MD, FACP
  • Cover Art & Infographic: Matthew Watto MD, FACP
  • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
  • Reviewer: Emi Okamoto MD
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
  • Technical Production: PodPaste
  • Guest: Yoo Mee Shin MD
Transcript Disclaimer
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