I have been listening to Fast Karate for at least 3 years now, and with every new show, there is always something new to laugh at. This podcast is the brain child of Dave Riley and Joel White, in which the two discuss games, anime, life, and sometimes food.
Normally, I wouldn't recommend a podcast like this, but the chemistry between these two hosts is second to none. They are comprable to Johnny Carson and Ed McMahon, except with each taking center stage instead of one being a sidekick.
They have a very loose format to their show, with a deceptive ammount of structure. But the best part of this podcast is that they understand what radio or talk is all about. The theatre of the mind. Their comedy stylings will keep you laughing all the way to work, and on the way back, with witty banter and whacky scenarios.
Take one listen, and I you will likely come back for another episode, then another one. Before you know it, you are hooked.