The good news is that this podcast provides some of the most insightful Lost theories and information available. I'm not aware of any other podcast that will give you this level of analysis and detail about the show.
The bad news is that if you feel like a bit of a dork for listening to a Lost podcast at all, this certainly isn't going to make you feel any cooler. Imagine being a fly on the wall in some 40 year old guy's parents' basement as a bunch of vintage geeks pontificate on Lost, and you've got a pretty good idea of what the podcast is like. That's actually not much of an exaggeration, as the podcast is pretty lo-tech, lo-res, and comments are not directed at the listener at all, and are instead directed at one another. Listening is like really lame voyeurism.
With that said, however, I still listen and I always come away with it with things I hadn't considered, because these folks REALLY know their stuff. Only you can determine whether wading through the unfathomable nerdiness is worth it. For me, it is.