I've been listening to the Matt & Ramona show for years, and have been thrilled to be able to listen podcasts at work. The recent format changes at their parent radio station have hurt the show content-wise, and I hope those changes don't stick. Greater Media: you will only lose your talent if you limit them like this.
The recent "improvements" to the podcast editing resulted in a greatly reduced bit rate, which iOS 4.3 won't play. If you listen to these podcasts on your iPhone, iPod, etc running 4.3, you have to convert them to AAC format first (right-click, then select Convert to AAC), THEN copy the new files over to a playlist from the Music library, where they are imported. The original Podcast files will still be 16 kbps MPEG-2.
Hopefully, the parent company wises up and upgrades their bit rate. 16 kbps sounds terrible on any speaker or earphone.