April 7, 2026

244: The Metabolic Root of Depression, Anxiety, & Mental Illness - Dr. Lori Calabrese

Dr. Lori Calabrese is a psychiatrist whose trajectory changed when a patient with 15 years of treatment-resistant anorexia went into full remission after a ketogenic diet. What followed was a research journey — pilot studies, peer-reviewed case series, and a now-funded randomized controlled trial — consistently showing that depression, anxiety, OCD, bipolar disorder, and other conditions could achieve complete remission, not just symptom reduction, through metabolic intervention. The key mech...

Also available on Apple Podcasts ↗